Key Factors
Jardiance is a sodium-glucose -cotransporter-2 (SGLT-2) inhibitor, which is utilized as a supplement to exercising and diet to regulate the blood sugar (sugar) in patients with diabetics of type 2. It lowers blood sugar levels by blocking kidney proteins to enhance the elimination of glucose through the urine.
Jardiance reduces the risk of dying from heart disease (like stroke or heart attack) in people who suffer from heart disease and reduces the likelihood of hospitalization as well as death due to failing heart (when you have a weak heart and is unable to provide enough blood flow to the rest part of your body) in patients suffering from heart failure.
For details on the Jardiance assistance program visit this website.
In time, elevated blood sugar levels could cause plaque to build within your blood vessels, increasing your risk for heart disease.
How does Jardiance perform?
Jardiance (empagliflozin) is classified as an SGLT-2 (sodium-glucose cotransporter-2) inhibitor. These proteins are found inside the kidney tubules that line the kidneys. They’re responsible for returning glucose into the blood. Jardiance inhibits the function on the proteins SGLT-2. This means that more glucose is excreted from the urine.
SGLT-2 inhibitors have been proven to be effective at lowering hemoglobin A1C levels which can aid in weight loss as well as in lowering blood pressure.
Jardiance can be added to other medicines used to treat type 2 diabetes, such as pioglitazone and metformin as well as sulfony and insulin as with other heart-related medications such as statins, beta blockers, ACE inhibitors and diuretics.
When used alone, SGLT-2 inhibitors carry a low risk of hyperglycemia (low glucose levels). However, your doctor might need to lower your dose of Jardiance in the event that you use it along with other medications that also cause low blood sugar, like insulin or Sulfonylureas.
Other FDA approved drugs in the SGLT-2 inhibitor class include:
canagliflozin (Invokana)
dapagliflozin (Farxiga)
ertugliflozin (Steglatro)
These medicines come as single-ingredient products , or when combined with other diabetes medicines
What can Jardiance help me with my diabetes type 2?
In type 2 diabetes your body isn’t producing enough insulin, the insulin that you make does not work as well and can cause too much sugar (sugar). When this happens, glucose builds up in your blood , which can lead to serious health conditions with the heart, kidney blood vessels, nerves and eyes. Training, diet, and use of special medications can help to lower your blood sugar levels and decrease the risk from developing type 2 diabetes.
A lot of patients who are recognized as having type 2 diabetes are with an oral medication referred to as metformin. It’s a class of drugs referred to as biguanides. It enhances the capacity of cells to use glucose (blood sugar) by improving the way your insulin functions and reduces the absorption of glucose from your liver.
Some patients are unable to attain their blood sugar goals without metformin and may require an additional dose of medication.
Jardiance is a supplement to metformin or other medicines to help you achieve your A1C goal. A1C is an easy blood test that measures the average quantity of sugar (glucose) in your blood over the last 2 to 3 months, letting you know how well your blood sugar is being controlled over time.
Who shouldn’t use Jardiance?
Jardiance should not be utilized in patients suffering from insulin resistance or with diabetic ketoacidosis (increased ketones found in urine or in the blood). In patients suffering from type 1 diabetes may increase the risk of diabetic ketoacidosis among these patients.
It is not recommended to use Jardiance in the event that you have a history of an extreme allergic reaction to Jardiance of any of its components.
You also should not use this drug if your condition is serious renal (renal) disease end-stage renal impairment, or suffer from dialysis. Your physician will examine your kidney function prior to you start treatments with Jardiance. Jardiance is not a good option for you if you have serious kidney problems.
What can I do to take Jardiance?
Take Jardiance at least once a day according to what your doctor has instructed you to do. It is available as a 20 mg and 25 mg tablets you take.
The recommended dose of Jardiance should be 10 milligrams daily in the morning, either with or without food. If you’re experiencing a mild reaction to Jardiance, the dose may increase to 25 mg if you require it.
Your doctor will test your kidney function using an examination of your blood before you start treatment. If you suffer from a particular amount of kidney disease you might not be able Jardiance.
Don’t take Jardiance in case you are allergic towards any component of it.
Jardiance is not suitable for use by anyone less than 18 years old.
The most important side effects of Jardiance
The majority of people tolerate Jardiance. However, like all drugs, there are significant side effects that you must discuss and review the effects with your physician.
The most serious side effects associated with Jardiance could be:
Ketoacidosis (increased ketones in urine or your blood)
Sudden kidney injury
Urinary tract infections
It is a condition that causes dehydration (the loss of body’s water and salt)
Low blood sugar (hypoglycemia)
Necrotizing fasciitis (a very rare but serious infection of the skin that can develop around the anus and the genitals)
Allergic reactions
More cholesterol
The most commonly reported adverse effects (5 5 percent or more) that can occur in Jardiance are:
Urinary tract infections
Yeast infections